Dr. Philippa C. Marrack is the chair of the Biomedical Research Department at National Jewish Health, a distinguished professor of Immunology & Microbiology in the Department of Immunology and Microbiology at the University of Colorado, and a Howard Hughes Medical Institute investigator.
Dr. Marrack's accomplishments include isolation of the T cell receptor and characterization of how autoreactive T cells are destroyed in the thymus. She also discovered superantigens, toxins that cause overwhelming and disastrous immune responses like in toxic shock syndrome. For these contributions, she was awarded the 1993 William B. Coley Award for Distinguished Research in Basic and Tumor Immunology, the Lifetime Achievement Award from the American Association of Immunologists, and has been elected to both the National Academy of Sciences and the Royal Society of London. She continues to focus on characterizing how our immune cells recognize antigens during normal immune responses as well as abnormal autoimmune reactions.
Dr. Marrack has been a member of CRI’s Scientific Advisory Council since 1986.
We study how vaccines [stimulate the ability of T cells to attack invaders], with the hope that this understanding will help us design better vaccines.
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